Prince Frederik of Luxembourg, child of Prince Robert and Princess Julie of Nassau, passed ahead on March 1 in Paris at the age of 22 after a longtime struggle with POLG nuclear condition.
His household confirmed the news in an personal statement on the POLG Foundation’s site. ” It is with a very large heart that my wife and I would like to inform you of the passing of our child, The POLG Foundation leader and artistic director, Frederik”, Prince Robert wrote.
Frederik was diagnosed with POLG nuclear condition at age 14 after decades of unknown health challenges. The rare genetic condition affects the body’s ability to produce electricity, leading to organ failure.
Despite his treatment, Frederik dedicated his life to advocating for study and knowledge. In his last events, Frederik called his loved ones to his side to say farewell. ” Frederik found the strength and the courage to say goodbye to each of us in convert”, Prince Robert said. ” Even in his last moments, his humour and boundless compassion compelled him to leave us with one last laugh … to cheer us all up”.
Frederik’s wellness had declined in recent days after being hospitalised with asthma and another serious illness.
Yet in his last days, Frederik continued to engage with the world. His parents recalled that he still had his concern set for an Italian lesson on Duolingo.
His home, struggling with his loss, are holding onto his thoughts. ” Come outside when the sun is shining”, he had written in a statement on his cellphone.
What is POLG
POLG disorder is a genetic condition that prevents the body from producing sufficient strength, leading to tissue loss. It is caused by abnormalities in the POLG and POLG2 alleles, which affect mitochondria—the brain’s energy source. Signs vary but typically include muscles failure, seizures, and kidney failure. There is no solution, and the condition worsens over time.
Once thought to be unique, the condition now influence about 1 in 5, 000 people widespread, making them the second most common major genetic condition after cystic fibrosis.
